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Today the Danish National Board of Health is reporting that data from a large registry study launched by the Danish National Board of Health suggest that the risk of malformations in children is slightly increased in women who were treated in early pregnancy with a selective serotonin reuptake inhibitors (SSRIs) antidepressant. Familiar SSRIs include Zoloft, Prozac, Paxil, Celexa and Lexapro. As a result of this new study the Danish National Board of Health maintains its recommendation that the decision to medically treat depression in pregnant women should be made only in consultation with a specialist in psychiatry and after other non-medical options have been considered.

Review of the safety of SSRIs in pregnant women

The review of earlier studies showed an increase in birth defects affecting the in the cardiovascular system in newborns whose mothers had been treated with Prozac and Paxil in the first trimester. Based on the present knowledge, the conclusion was that similar defects, especially heart malformations, could be associated with Zoloft, Celexa and other SSRIs.

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